{"id":3682,"date":"2020-03-23T16:04:01","date_gmt":"2020-03-23T09:04:01","guid":{"rendered":"http:\/\/new.vientebaogoc.edu.vn\/?post_type=blog_post&p=1176"},"modified":"2024-11-24T07:58:41","modified_gmt":"2024-11-24T00:58:41","slug":"buong-trung-duoc-tao-ra-tu-cong-nghe-in-3d-co-the-phuc-hoi-kha-nang-sinh-san-tren-chuot","status":"publish","type":"post","link":"https:\/\/sci.edu.vn\/home\/blog\/2020\/03\/23\/buong-trung-duoc-tao-ra-tu-cong-nghe-in-3d-co-the-phuc-hoi-kha-nang-sinh-san-tren-chuot\/","title":{"rendered":"Bu\u1ed3ng tr\u1ee9ng \u0111\u01b0\u1ee3c t\u1ea1o ra t\u1eeb c\u00f4ng ngh\u1ec7 in 3D c\u00f3 th\u1ec3 ph\u1ee5c h\u1ed3i kh\u1ea3 n\u0103ng sinh s\u1ea3n tr\u00ean chu\u1ed9t"},"content":{"rendered":"\n

B\u00e2y gi\u1edd b\u1ea1n c\u00f3 th\u1ec3 in c\u00e1c c\u01a1 quan b\u1eb1ng c\u00f4ng ngh\u1ec7 in 3D. Tr\u00ean th\u1ef1c t\u1ebf, c\u00e1c c\u1ea5u tr\u00fac bu\u1ed3ng tr\u1ee9ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c in theo c\u00e1ch t\u01b0\u01a1ng t\u1ef1 \u0111\u1ec3 t\u1ea1o ra m\u1ed9t bu\u1ed3ng tr\u1ee9ng gi\u1ed1ng thi\u1ebft k\u1ebf c\u1ee7a bu\u1ed3ng tr\u1ee9ng th\u1eadt. M\u1ed9t nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i Tr\u01b0\u1eddng Y khoa Feinberg, Tr\u01b0\u1eddng K\u1ef9 thu\u1eadt McCormick, thu\u1ed9c Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc Northwestern, \u0111\u00e3 cho th\u1ea5y bu\u1ed3ng tr\u1ee9ng chu\u1ed9t t\u1eeb c\u00f4ng ngh\u1ec7 in 3D c\u00f3 th\u1ec3 ph\u1ee5c h\u1ed3i sinh s\u1ea3n \u1edf chu\u1ed9t. K\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u00ean t\u1ea1p ch\u00ed Nature Communications.<\/strong><\/em><\/strong><\/p>\n\n\n\n

\"\"
Bu\u1ed3ng tr\u1ee9ng v\u00e0 chu\u1ed9t \u0111\u01b0\u1ee3c sinh ra t\u1eeb chu\u1ed9t m\u1eb9 c\u1ea5y bu\u1ed3ng tr\u1ee9ng nh\u00e2n t\u1ea1o t\u1eeb c\u00f4ng ngh\u1ec7 in 3D. <\/strong><\/em><\/strong><\/figcaption><\/figure>\n\n\n\n


L\u00e0m th\u1ebf n\u00e0o bu\u1ed3ng tr\u1ee9ng in 3D  c\u00f3 th\u1ec3 sinh s\u1ea3n?<\/strong>

<\/em><\/strong>Bu\u1ed3ng tr\u1ee9ng c\u1ee7a chu\u1ed9t c\u00e1i \u0111\u01b0\u1ee3c thay th\u1ebf b\u1eb1ng bu\u1ed3ng tr\u1ee9ng in 3D. Chu\u1ed9t sau \u0111\u00f3 c\u00f3 th\u1ec3 r\u1ee5ng tr\u1ee9ng v\u00e0 th\u1eadm ch\u00ed sinh con. Chu\u1ed9t m\u1eb9 c\u0169ng c\u00f3 th\u1ec3 nu\u00f4i con. C\u00e1c bu\u1ed3ng tr\u1ee9ng sinh l\u00fd \u0111\u01b0\u1ee3c x\u00e2y d\u1ef1ng v\u1edbi gi\u00e0n gi\u00e1o in 3D ch\u1ee9a tr\u1ee9ng chu\u1ed9t ch\u01b0a tr\u01b0\u1edfng th\u00e0nh. Nh\u1eefng bu\u1ed3ng tr\u1ee9ng n\u00e0y \u0111\u00e3 t\u0103ng s\u1ea3n xu\u1ea5t hoocmon v\u00e0 ph\u1ee5c h\u1ed3i kh\u1ea3 n\u0103ng sinh s\u1ea3n.<\/p>\n\n\n\n

T\u1ea1i sao nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 quan tr\u1ecdng?<\/strong>

<\/em><\/strong>Nghi\u00ean c\u1ee9u n\u00e0y ch\u1ee9ng minh r\u1eb1ng bu\u1ed3ng tr\u1ee9ng in 3D c\u00f3 ch\u1ee9c n\u0103ng nh\u01b0 bu\u1ed3ng tr\u1ee9ng b\u00ecnh th\u01b0\u1eddng. N\u1ebfu \u0111i\u1ec1u n\u00e0y th\u00e0nh c\u00f4ng tr\u00ean ng\u01b0\u1eddi s\u1ebd tr\u1edf th\u00e0nh m\u1ed9t b\u01b0\u1edbc ti\u1ebfn m\u1edbi. Nhu c\u1ea7u s\u1eed d\u1ee5ng x\u00e1c ch\u1ebft l\u1ea5y c\u01a1 quan \u0111\u1ec3 kh\u00f4i ph\u1ee5c c\u00e1c m\u00f4 kh\u1ecfe m\u1ea1nh \u1edf b\u1ec7nh nh\u00e2n s\u1ebd kh\u00f4ng c\u1ea7n thi\u1ebft. \u0110\u00e2y l\u00e0 b\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc y h\u1ecdc t\u00e1i t\u1ea1o.<\/p>\n\n\n\n

T\u1ea1i sao nghi\u00ean c\u1ee9u n\u00e0y \u0111\u1ed9c \u0111\u00e1o?<\/strong>

<\/em><\/strong>Nghi\u00ean c\u1ee9u n\u00e0y kh\u00e1c v\u1edbi nghi\u00ean c\u1ee9u c\u1ee7a c\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m kh\u00e1c v\u00ec thi\u1ebft k\u1ebf c\u1ee7a gi\u00e1 th\u1ec3 (scaffold) v\u00e0 v\u1eadt li\u1ec7u (m\u1ef1c in) \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 cao. V\u1eadt li\u1ec7u \u0111\u01b0\u1ee3c l\u00e0m t\u1eeb gelatin, hydrogel sinh h\u1ecdc \u0111\u01b0\u1ee3c t\u1ea1o ra v\u1edbi collagen an to\u00e0n \u0111\u1ec3 s\u1eed d\u1ee5ng \u1edf ng\u01b0\u1eddi. Nh\u00f3m nghi\u00ean c\u1ee9u bi\u1ebft r\u1eb1ng gi\u00e1 th\u1ec3 ph\u1ea3i bao g\u1ed3m v\u1eadt li\u1ec7u h\u1eefu c\u01a1 \u0111\u1ee7 r\u1eafn \u0111\u1ec3 \u0111\u01b0\u1ee3c x\u1eed l\u00fd trong ph\u1eabu thu\u1eadt v\u00e0 \u0111\u1ee7 x\u1ed1p \u0111\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c m\u00f4 c\u01a1 th\u1ec3. H\u1ecd s\u1eed d\u1ee5ng m\u1ed9t gelatin t\u1ef1 h\u1ed7 tr\u1ee3 v\u00e0 c\u00f3 kh\u1ea3 n\u0103ng x\u00e2y d\u1ef1ng m\u1ed9t v\u00e0i l\u1edbp. <\/em><\/strong>S\u1ef1 h\u1ed7 tr\u1ee3 n\u00e0y l\u00e0m cho c\u00e1c nang tr\u1ee9ng v\u00e0 t\u1ebf b\u00e0o tr\u1ee9ng xung quanh t\u1ebf b\u00e0o tr\u1ee9ng ch\u01b0a tr\u01b0\u1edfng th\u00e0nh c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i trong bu\u1ed3ng tr\u1ee9ng. T\u00f3m l\u1ea1i, \u0111\u00e2y l\u00e0 nghi\u00ean c\u1ee9u \u0111\u1ea7u ti\u00ean cho th\u1ea5y c\u1ea5u tr\u00fac gi\u00e1 th\u1ec3 t\u1ea1o ra s\u1ef1 kh\u00e1c bi\u1ec7t c\u00f3 \u00fd ngh\u0129a trong s\u1ef1 s\u1ed1ng c\u00f2n c\u1ee7a nang tr\u1ee9ng. \u0110i\u1ec1u n\u00e0y s\u1ebd kh\u00f4ng th\u1ec3 x\u1ea3y ra n\u1ebfu kh\u00f4ng c\u00f3 m\u00e1y in 3D.<\/p>\n\n\n\n


Ph\u01b0\u01a1ng ph\u00e1p nghi\u00ean c\u1ee9u cho con ng\u01b0\u1eddi<\/strong>

<\/em><\/strong>M\u1ee5c ti\u00eau ch\u00ednh c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc trong vi\u1ec7c t\u1ea1o ra bu\u1ed3ng tr\u1ee9ng l\u00e0 thay \u0111\u1ed5i hoocmon v\u00e0 kh\u1ea3 n\u0103ng sinh s\u1ea3n \u1edf nh\u1eefng ph\u1ee5 n\u1eef \u0111\u00e3 t\u1eebng tr\u1ea3i qua c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00e0 ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 v\u00f4 sinh cao.

Gi\u00e1 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nghi\u00ean c\u1ee9u n\u00e0y nh\u1eb1m m\u1ee5c \u0111\u00edch m\u00f4 t\u1ea3 c\u00e1ch th\u1ee9c m\u00e0 bu\u1ed3ng tr\u1ee9ng ho\u1ea1t \u0111\u1ed9ng. N\u00f3 c\u00f3 th\u1ec3 ph\u1ee5c v\u1ee5 m\u1ee5c \u0111\u00edch n\u00e0y t\u1eeb tu\u1ed5i d\u1eady th\u00ec, v\u00e0o tu\u1ed5i tr\u01b0\u1edfng th\u00e0nh, m\u00e3n kinh v\u00e0 h\u01a1n th\u1ebf n\u1eefa.<\/p>\n\n\n\n

(Ph\u1ea1m V\u0169)<\/em><\/strong><\/p>\n\n\n\n

\u0110\u1ecdc th\u00eam t\u1ea1i:<\/em><\/strong><\/p>\n\n\n\n

https:\/\/www.nature.com\/articles\/ncomms15261<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

B\u00e2y gi\u1edd b\u1ea1n c\u00f3 th\u1ec3 in c\u00e1c c\u01a1 quan b\u1eb1ng c\u00f4ng ngh\u1ec7 in 3D. Tr\u00ean th\u1ef1c t\u1ebf, c\u00e1c c\u1ea5u tr\u00fac bu\u1ed3ng tr\u1ee9ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c in theo c\u00e1ch t\u01b0\u01a1ng t\u1ef1 \u0111\u1ec3 t\u1ea1o ra m\u1ed9t bu\u1ed3ng tr\u1ee9ng gi\u1ed1ng thi\u1ebft k\u1ebf c\u1ee7a bu\u1ed3ng tr\u1ee9ng th\u1eadt. M\u1ed9t nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i Tr\u01b0\u1eddng Y khoa Feinberg, Tr\u01b0\u1eddng […]<\/p>\n","protected":false},"author":293,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[161],"tags":[],"class_list":["post-3682","post","type-post","status-publish","format-standard","hentry","category-ban-tin"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/users\/293"}],"replies":[{"embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/comments?post=3682"}],"version-history":[{"count":1,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3682\/revisions"}],"predecessor-version":[{"id":4473,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3682\/revisions\/4473"}],"wp:attachment":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/media?parent=3682"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/categories?post=3682"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/tags?post=3682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}