{"id":3687,"date":"2020-08-17T10:22:58","date_gmt":"2020-08-17T03:22:58","guid":{"rendered":"http:\/\/sci.edu.vn\/?post_type=blog_post&p=1565"},"modified":"2024-11-24T08:12:02","modified_gmt":"2024-11-24T01:12:02","slug":"thuoc-te-bao-goc-dot-pha-cong-nghe-cua-vien-te-bao-goc-2","status":"publish","type":"post","link":"https:\/\/sci.edu.vn\/home\/blog\/2020\/08\/17\/thuoc-te-bao-goc-dot-pha-cong-nghe-cua-vien-te-bao-goc-2\/","title":{"rendered":"Thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c – \u0110\u1ed9t ph\u00e1 c\u00f4ng ngh\u1ec7 c\u1ee7a Vi\u1ec7n T\u1ebf b\u00e0o g\u1ed1c"},"content":{"rendered":"\n

T\u1ebf b\u00e0o g\u1ed1c l\u00e0 m\u1ed9t l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb m\u1edbi trong y h\u1ecdc. T\u1ebf b\u00e0o g\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng ng\u00e0y c\u00e0ng nhi\u1ec1u \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh. Trong th\u1ef1c t\u1ebf, ng\u00e0nh khoa h\u1ecdc nghi\u00ean c\u1ee9u t\u1ebf b\u00e0o g\u1ed1c \u0111\u00e3 th\u00fac \u0111\u1ea9y m\u1ed9t th\u1eddi \u0111\u1ea1i m\u1edbi c\u1ee7a y h\u1ecdc \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 y h\u1ecdc t\u00e1i t\u1ea1o. Trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, y h\u1ecdc t\u00e1i t\u1ea1o \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t cu\u1ed9c c\u00e1ch m\u1ea1ng m\u1edbi trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh, \u0111\u1eb7c bi\u1ec7t l\u00e0 v\u1edbi vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c. Thu\u1ed1c g\u1ed1c t\u1ebf b\u00e0o g\u1ed1c l\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m ch\u1ee9a t\u1ebf b\u00e0o g\u1ed1c s\u1ed1ng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng l\u00e0m thu\u1ed1c cho c\u00e1c b\u1ec7nh c\u1ee5 th\u1ec3. Kh\u00f4ng gi\u1ed1ng nh\u01b0 quy tr\u00ecnh c\u1ea5y gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c t\u1ef1 th\u00e2n, c\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c g\u1ed1c t\u1ebf b\u00e0o l\u00e0 nh\u1eefng s\u1ea3n ph\u1ea9m “s\u1eb5n s\u00e0ng s\u1eed d\u1ee5ng<\/em><\/strong>” hay c\u00f2n g\u1ecdi l\u00e0 \u201coff-the-shelf<\/em><\/strong>\u201d ngh\u0129a kh\u00f4ng c\u1ea7n ph\u1ea3i th\u00eam thao t\u00e1c n\u00e0o n\u1eefa \u0111\u1ec3 x\u1eed l\u00ed t\u1ebf b\u00e0o tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng t\u1ebf b\u00e0o g\u1ed1c.<\/p>\n\n\n\n

M\u1ed9t lo\u1ea1i thu\u1ed1c \u0111\u01b0\u1ee3c \u0111\u1ecbnh ngh\u0129a l\u00e0 b\u1ea5t k\u1ef3 ch\u1ea5t n\u00e0o kh\u00e1c th\u1ef1c ph\u1ea9m, khi h\u00edt, ti\u00eam, h\u00fat, ti\u00eau th\u1ee5, h\u1ea5p th\u1ee5 qua mi\u1ebfng d\u00e1n tr\u00ean da ho\u1eb7c tan d\u01b0\u1edbi l\u01b0\u1ee1i g\u00e2y ra s\u1ef1 thay \u0111\u1ed5i v\u1ec1 sinh l\u00fd trong c\u01a1 th\u1ec3. Trong d\u01b0\u1ee3c ph\u1ea9m, thu\u1ed1c (ho\u1eb7c d\u01b0\u1ee3c ph\u1ea9m) l\u00e0 m\u1ed9t ch\u1ea5t \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb, ng\u0103n ng\u1eeba ho\u1eb7c ch\u1ea9n \u0111o\u00e1n b\u1ec7nh ho\u1eb7c \u0111\u1ec3 th\u00fac \u0111\u1ea9y s\u1ef1 l\u00e0nh b\u1ec7nh. Theo \u0111\u1ecbnh ngh\u0129a n\u00e0y, m\u1ed9t lo\u1ea1i thu\u1ed1c ph\u1ea3i \u0111\u00e1p \u1ee9ng m\u1ed9t s\u1ed1 ti\u00eau ch\u00ed, ch\u1eb3ng h\u1ea1n nh\u01b0 c\u00f3 ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh v\u00e0 l\u00e0 m\u1ed9t s\u1ea3n ph\u1ea9m c\u00f3 ph\u1ea1m vi s\u1eed d\u1ee5ng c\u1ee5 th\u1ec3. Do \u0111\u00f3, theo \u0111\u1ecbnh ngh\u0129a, c\u00e1c lo\u1ea1i thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c l\u00e0 c\u00e1c s\u1ea3n ph\u1ea9m d\u1ef1a tr\u00ean c\u00e1c t\u1ebf b\u00e0o g\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb, ch\u1eefa b\u1ec7nh, ng\u0103n ng\u1eeba ho\u1eb7c ch\u1ea9n \u0111o\u00e1n b\u1ec7nh ho\u1eb7c \u0111\u1ec3 th\u00fac \u0111\u1ea9y s\u1ef1 l\u00e0nh b\u1ec7nh.<\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

H\u00ecnh 1<\/a>. C\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d v\u00e0 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c (stem cell drug) trong Y h\u1ecdc t\u00e1i t\u1ea1o. Thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c l\u00e0 s\u1ea3n ph\u1ea9m ti\u00eau bi\u1ec3u c\u1ee7a c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d trong l\u0129nh v\u1ef1c y h\u1ecdc t\u00e1i t\u1ea1o; \u0111\u01b0\u1ee3c v\u00ed nh\u01b0 \u0111i\u1ec7n tho\u1ea1i th\u00f4ng minh l\u00e0 s\u1ea3n ph\u1ea9m ti\u00eau bi\u1ec3u c\u1ee7a c\u00f4ng ngh\u1ec7 di \u0111\u1ed9ng.<\/em><\/p>\n\n\n\n

            Thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c l\u00e0 s\u1ea3n ph\u1ea9m ti\u00eau bi\u1ec3u c\u1ee7a c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d<\/strong>. C\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d l\u00e0 c\u00f4ng ngh\u1ec7 c\u1ed1t l\u00f5i v\u00e0 \u0111ang ph\u00e1t tri\u1ec3n m\u1ea1nh m\u1ebd. Ng\u01b0\u1eddi ta \u0111ang v\u00ed c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d nh\u01b0 c\u00f4ng ngh\u1ec7 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o v\u00e0 di \u0111\u1ed9ng. S\u1ea3n ph\u1ea9m ti\u00eau bi\u1ec3u c\u1ee7a c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d l\u00e0 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c (stem cell drugs) gi\u1ed1ng nh\u01b0 \u0111i\u1ec7n tho\u1ea1i th\u00f4ng minh l\u00e0 s\u1ea3n ph\u1ea9m ti\u00eau bi\u1ec3u c\u1ee7a c\u00f4ng ngh\u1ec7 tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o v\u00e0 di \u0111\u1ed9ng. S\u1ef1 kh\u00e1c bi\u1ec7t gi\u1eefa c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d v\u00e0 c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c truy\u1ec1n th\u1ed1ng \u0111\u01b0\u1ee3c tr\u00ecnh b\u00e0y trong B\u1ea3ng 1.<\/p>\n\n\n\n

              L\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c off-the-shelf, h\u1ea7u h\u1ebft thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong c\u00e1c quy tr\u00ecnh c\u1ea5y gh\u00e9p \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng lo\u00e0i. Tuy nhi\u00ean, c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t l\u1edbn gi\u1eefa quy tr\u00ecnh gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ed3ng lo\u00e0i v\u00e0 c\u00e1c thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c. S\u1ef1 kh\u00e1c bi\u1ec7t l\u1edbn nh\u1ea5t gi\u1eefa ch\u00fang l\u00e0 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c l\u00e0 m\u1ed9t s\u1ea3n ph\u1ea9m, trong khi quy tr\u00ecnh c\u1ea5y gh\u00e9p t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ed3ng lo\u1ea1i l\u00e0 m\u1ed9t th\u1ee7 thu\u1eadt hay quy tr\u00ecnh s\u1eed d\u1ee5ng t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ed3ng lo\u00e0i.<\/p>\n\n\n\n

B\u1ea3ng <\/a>1. So s\u00e1nh \u0111\u1eb7c \u0111i\u1ec3m c\u1ee7a 2 c\u00f4ng ngh\u1ec7: c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c th\u01b0\u1eddng v\u00e0 c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d<\/em><\/p>\n\n\n\n

\"\"<\/figure><\/div>\n\n\n\n

              C\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d<\/strong> \u0111\u01b0\u1ee3c b\u00f9ng n\u1ed5 b\u1edfi s\u1ef1 ra \u0111\u1eddi c\u1ee7a s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ea7u ti\u00ean th\u1ebf gi\u1edbi \u0111\u01b0\u1ee3c ch\u00ednh ph\u1ee7 Canada c\u1ea5p ph\u00e9p l\u01b0u h\u00e0nh trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh m\u1ea3nh gh\u00e9p ch\u1ed1ng k\u00ed ch\u1ee7 (GVHD) v\u00e0o n\u0103m 2012, \u0111\u00f3 l\u00e0 Prochymal (do c\u00f4ng ty Osiris Therapeutic, Canada nghi\u00ean c\u1ee9u v\u00e0 s\u1ea3n xu\u1ea5t). Ti\u1ebfp theo \u0111\u00f3, s\u1ef1 ra \u0111\u1eddi c\u1ee7a nhi\u1ec1u s\u1ea3n ph\u1ea9m kh\u00e1c c\u1ee7a m\u1ed9t s\u1ed1 qu\u1ed1c gia, trong \u0111\u00f3 ph\u1ea3i k\u1ec3 \u0111\u1ebfn nh\u01b0 Cartistem (H\u00e0n Qu\u1ed1c), Cupistem (H\u00e0n Qu\u1ed1c), Temcell HS (Nh\u1eadt)… \u0110\u1ebfn nay, m\u1ed9t s\u1ed1 qu\u1ed1c gia \u0111\u00e3 ph\u00e1t tri\u1ec3n th\u00e0nh c\u00f4ng c\u00f4ng ngh\u1ec7 t\u1ebf b\u00e0o g\u1ed1c \u201coff-the-shelf\u201d<\/strong> bao g\u1ed3m M\u0129, Nh\u1eadt, H\u00e0n Qu\u1ed1c, Canada, \u00dac, Trung Qu\u1ed1c, \u1ea4n \u0110\u1ed9 v\u00e0 \u0110\u1ee9c. Tuy nhi\u00ean, ch\u1ec9 c\u00f3 ba qu\u1ed1c gia Canada, H\u00e0n Qu\u1ed1c v\u00e0 Nh\u1eadt B\u1ea3n c\u00f3 s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c ph\u00e9p l\u01b0u h\u00e0nh trong n\u01b0\u1edbc. Nh\u1eefng s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a c\u00e1c qu\u1ed1c gia n\u00e0y \u0111ang \u0111\u01b0\u1ee3c xu\u1ea5t kh\u1ea9u r\u1ed9ng r\u00e3i tr\u00ean th\u1ebf gi\u1edbi. V\u00ed d\u1ee5 s\u1ea3n ph\u1ea9m Prochymal c\u1ee7a Canada \u0111\u00e3 xu\u1ea5t kh\u1ea9u \u0111\u1ebfn 12 qu\u1ed1c gia (k\u1ec3 c\u1ea3 M\u0129) nh\u1eb1m s\u1eed d\u1ee5ng trong \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh m\u1ea3nh gh\u00e9p ch\u1ed1ng k\u00ed ch\u1ee7. B\u00ean c\u1ea1nh l\u1ee3i \u00edch kinh t\u1ebf mang l\u1ea1i t\u1eeb vi\u1ec7c n\u00e0y, Prochymal \u0111ang cung c\u1ea5p m\u1ed9t thu\u1ed1c m\u1edbi trong \u0111i\u1ec1u tr\u1ecb b\u1ec7nh n\u00e0y.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

            Vi\u1ec7n T\u1ebf b\u00e0o g\u1ed1c<\/em><\/strong> b\u1eaft \u0111\u1ea7u ti\u1ebfp c\u1eadn c\u00f4ng ngh\u1ec7 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c t\u1eeb n\u0103m 2012. \u0110\u1ebfn nay, Vi\u1ec7n T\u1ebf b\u00e0o g\u1ed1c \u0111\u00e3 l\u00e0m ch\u1ee7 c\u00e1c c\u00f4ng ngh\u1ec7 c\u1ed1t l\u00f5i c\u1ee7a c\u00f4ng ngh\u1ec7 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c. C\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a Vi\u1ec7n th\u01b0\u1eddng s\u1eed d\u1ee5ng t\u1ebf b\u00e0o g\u1ed1c t\u1eeb m\u00f4 m\u1ee1, t\u1eeb d\u00e2y r\u1ed1n hay m\u00e1u d\u00e2y r\u1ed1n; c\u0169ng nh\u01b0 c\u00e1c exosome v\u00e0 t\u00fai ti\u1ebft t\u1eeb qu\u00e1 tr\u00ecnh nu\u00f4i c\u1ea5y c\u00e1c t\u1ebf b\u00e0o g\u1ed1c n\u00e0y.<\/p>\n\n\n\n

            Vi\u1ec7n \u0111\u00e3 nghi\u00ean c\u1ee9u v\u00e0 ph\u00e1t tri\u1ec3n th\u00e0nh c\u00f4ng c\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c nh\u01b0: Cartilatist, Modulatist, Skinatist v\u00e0 Vasculatist<\/span><\/em><\/strong>. S\u1ea3n ph\u1ea9m Cartilatist l\u00e0 s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c \u0111\u1ea7u ti\u00ean c\u1ee7a Vi\u1ec7n, \u1ee9ng d\u1ee5ng trong quy tr\u00ecnh \u0111i\u1ec1u tr\u1ecb tho\u00e1i ho\u00e1 kh\u1edbp, tho\u00e1i ho\u00e1 \u0111\u0129a \u0111\u1ec7m c\u1ed9t s\u1ed1ng. Modulatist l\u00e0 s\u1ea3n ph\u1ea9m s\u1eed d\u1ee5ng trong quy tr\u00ecnh \u0111i\u1ec1u tr\u1ecb c\u00e1c b\u1ec7nh l\u00ed vi\u00eam m\u1ea1n t\u00ednh v\u00e0 c\u1ea5p t\u00ednh nh\u01b0 b\u1ec7nh ph\u1ed5i t\u1eafc ngh\u1ebdn m\u1ea1n t\u00ednh, b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng\u2026 Trong khi \u0111\u00f3 Vasculatist l\u00e0 s\u1ea3n ph\u1ea9m s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o v\u00e0 y\u1ebfu t\u1ed1 k\u00edch th\u00edch t\u00e1i t\u1ea1o m\u1ea1ch m\u00e1u trong b\u1ec7nh l\u00ed t\u1eafc m\u1ea1ch. S\u1ea3n ph\u1ea9m Skinatist l\u00e0 m\u1ed9t th\u1ebf h\u1ec7 s\u1ea3n ph\u1ea9m kh\u00e1c v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m c\u00f2n l\u1ea1i. Skinatist ch\u1ee9a c\u00e1c t\u00fai ti\u1ebft t\u1eeb t\u1ebf b\u00e0o g\u1ed1c, kh\u00f4ng ch\u1ee9a t\u1ebf b\u00e0o g\u1ed1c. S\u1ea3n ph\u1ea9m n\u00e0y s\u1eed d\u1ee5ng trong quy tr\u00ecnh \u0111i\u1ec1u tr\u1ecb b\u1ecfng, lo\u00e9t l\u00e2u l\u00e0nh, lo\u00e9t \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng.<\/p>\n\n\n\n

            Xem th\u00eam th\u00f4ng tin s\u1ea3n ph\u1ea9m trong brochure thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a Vi\u1ec7n.<\/strong><\/p>\n\n\n\n

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T\u1ea3i Stem-cell-drug-brochure <\/strong><\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Vi\u1ec7n T\u1ebf b\u00e0o g\u1ed1c b\u1eaft \u0111\u1ea7u ti\u1ebfp c\u1eadn c\u00f4ng ngh\u1ec7 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c t\u1eeb n\u0103m 2012. \u0110\u1ebfn nay, Vi\u1ec7n T\u1ebf b\u00e0o g\u1ed1c \u0111\u00e3 l\u00e0m ch\u1ee7 c\u00e1c c\u00f4ng ngh\u1ec7 c\u1ed1t l\u00f5i c\u1ee7a c\u00f4ng ngh\u1ec7 thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c. C\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a Vi\u1ec7n th\u01b0\u1eddng s\u1eed d\u1ee5ng t\u1ebf b\u00e0o g\u1ed1c t\u1eeb m\u00f4 m\u1ee1, t\u1eeb d\u00e2y r\u1ed1n hay m\u00e1u d\u00e2y r\u1ed1n; c\u0169ng nh\u01b0 c\u00e1c exosome v\u00e0 t\u00fai ti\u1ebft t\u1eeb qu\u00e1 tr\u00ecnh nu\u00f4i c\u1ea5y c\u00e1c t\u1ebf b\u00e0o g\u1ed1c n\u00e0y.<\/p>\n","protected":false},"author":291,"featured_media":1569,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[161],"tags":[72,77],"class_list":["post-3687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ban-tin","tag-sci","tag-stemcelldrugs"],"jetpack_featured_media_url":"https:\/\/sci.edu.vn\/home\/wp-content\/uploads\/2020\/08\/thuoc1.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/users\/291"}],"replies":[{"embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/comments?post=3687"}],"version-history":[{"count":2,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3687\/revisions"}],"predecessor-version":[{"id":4698,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/posts\/3687\/revisions\/4698"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/media\/1569"}],"wp:attachment":[{"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/media?parent=3687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/categories?post=3687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sci.edu.vn\/home\/wp-json\/wp\/v2\/tags?post=3687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}